Clinic Study

In 2009, we engaged the Shanghai Institute of Stomatology (上海市口腔研究所) to conduct a clinical study to evaluate the efficacy and safety of our functional toothpaste. The study period was 6 months and it involved 160 participants aged between 21 and 48. The participants were equally divided into a control group and a trial group, where the control group was provided with toothpaste without any biological enzyme while the trial group was provided with our functional toothpaste. According to the clinical report, it was found that the test result of the trial group was significantly better than that of the control group because our functional toothpaste could effectively suppress and prevent oral problems such as teeth bleeding, periodontitis and gingivitis, improve periodontal health and whiten teeth.


In 2009, we also engaged the Shanghai Municipal Centre for Disease Control and Prevention (上海市疾病預防控制中心) , the Shanghai Institutes of Preventive Medicine (上海市預防醫學研究院) and the Shanghai Disease Control, Safety and Health Care Evaluation Centre (上海疾控安全健康保健評價中心) to conduct a study on hamsters to evaluate the toxicity and the oral mucosa stimulation of our functional toothpaste. According to the report, it was found that our functional toothpaste was nontoxic and of very light oral mucosa stimulation.


In 2012 and 2015 respectively, we engaged the Shanghai Ninth People’s Hospital,Shanghai JiaoTong University School of Medicine (上海交通大學醫學院附屬第九人民醫院) to conduct clinical studies to further verify the anti-cavity effect and aphthous ulcer treatment effect of our functional toothpaste. The clinical study conducted in 2012 involved 70 participants over a period of eight weeks while the clinical study conducted in 2015 involved 71 participants over a period of 12 weeks. The participants were divided into a control group and a trial group, where the control group was provided with toothpaste without any biological enzyme while the trial group was provided with our functional toothpaste during the study period. The clinical study conducted in 2012 showed that our functional toothpaste has the effect of reducing dentin hypersensitivity, is safe to use and does not cause any negative effects. Similarly, the clinical study conducted in 2015 showed that our functional toothpaste is safe to use and has the effect of easing mouth ulcers, facilitating the healing of mouth ulcers, repairing damaged oral mucosa, and reducing recurrent of oral ulcers.


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